The first chemical synthesis of boronic acid-modified DNA through a copper-free click reaction.

نویسندگان

  • Chaofeng Dai
  • Lifang Wang
  • Jia Sheng
  • Hanjing Peng
  • Alexander Boryanov Draganov
  • Zhen Huang
  • Binghe Wang
چکیده

The first chemical incorporation of the boronic acid group into DNA using a copper-free click reagent was reported. Compared with the PCR-based method, this approach allows for site-specific incorporation and synthesis on a larger scale.

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عنوان ژورنال:
  • Chemical communications

دوره 47 12  شماره 

صفحات  -

تاریخ انتشار 2011